Respiratory pathogens panel / Test # 6675

Background:
Respiratory viruses are responsible for a wide range of acute respiratory tract infections including the common cold, influenza, and croup. Disease severity can be especially high in the young, the immunocompromised, and elderly patients. Respiratory illnesses caused by influenza virus infection are difficult to distinguish from illnesses caused by other respiratory pathogens on the basis of signs and symptoms alone.1 Adults average 2-5 Upper Respiratory Tract Infections (URTI), while children average 7-10 URTIs per year.2 Overlapping signs and symptoms include: coughing, nasal discharge, congestion, fever, wheezing, headache and myalgia.

Antibiotics are often prescribed to treat URTIs, however the CDC estimates that 50% of antibiotic prescriptions are unnecessary as most of these infections are caused by a virus.3 This results in approximately $1 billion annually in unnecessary adult URTI antibiotic prescriptions.4

What is Respiratory Pathogens Panel?

Lenco’s Respiratory Pathogens Panel is FDA-cleared and provides an overall sensitivity and specificity of 95% and 99%, respectively. Rapid and accurate diagnostic testing for 21 respiratory pathogens may help identify which patients to isolate or cohort faster and determine if antibiotic or antiviral therapy is appropriate.

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Why Respiratory Pathogens Panel?

Our Respiratory Pathogens Panel increases the probability of identifying a pathogen correctly, the first time with 17 viral targets and 4 bacterial targets from a single specimen.

  • Comprehensive, accurate, and fast results Improve patient management
  • Prevent secondary spread of infection
  • Reduce the unwarranted use of antibiotics
  • Provide more timely and accurate treatment

Who can be tested?

All patients with signs/symptoms (syndrome) suggestive of a respiratory tract infection.

  • Adults 65+
  • Children under 5
  • Anyone with symptoms of co-infection
  • Immunocompromised patients (chemo, HIV, Bone marrow/organ transplant, hematologic disorders)

Specimen Requirements:

Submit one (1) Nasopharyngeal Swab in Viral Transport Media (M4) ~ 300 µl of sample is required for testing.

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Transport/Stability:

Room temperature specimen is stable for 4 hours. Refrigerated specimen is stable for 3 days.
Frozen specimen is stable for 30 days. Unlabeled, mislabeled, or mismatched specimen is unacceptable.

References:

  1. CDC, Clinical Signs and Symptoms of Influenza 2009.
  2. Johnston S, Holgate S. Epidemiology of viral respiratory infections. In: Myint S, Taylor-Robinson D, eds. Viral and other infections of the human respiratory tract. London: Chapman & Hall, 1996: 1-38.
  3. Proceedings from the National Summit on Overuse; September 24, 2012. Organized by The Joint Commission and the American Medical Association Convened Physician Consortium for Performance Improvement® (PCPI®).
  4. Goka et al. (2012) Influenza A viruses dual and multiple infections with other respiratory viruses and risk of hospitalisation and a mortality. Influenza and Other Respiratory Viruses DOI: 10.1111/ irv.12020.